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[Laughs] ‘It was certainly an excellent threat! At the time, I was well knowledgeable that it could go Completely wrong Which I could turn into a lot less productive, but I just dismissed that. Curiosity has usually been my strongest driving drive. And luckily everything worked out.’
2007, first true-time detection of strand Trade in homologous recombination by RecA; discovery of a minimal persistence duration of ends of microtubules; and settled the system of biosensing with carbon nanotubes
This yielded a breakthrough. Within just just a few months, we were being capable to measure transport through someone one-walled carbon nanotube. Determined by low-temperature experiments by an excellent PhD student in my team, Sander Tans (now a valued colleague and professor at Delft University of Technological know-how using an Lively investigation lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes were authentic quantum wires with very very long (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic behaviour.
Microbiology has only been around for your century, considering the fact that we began to study micro-organisms much more critically. I thought nanobiology was an proper phrase, due to the fact all molecular Organic suitable interactions occur for the nanoscale: a protein is a handful of nanometres in measurement, DNA is 2 nm thick.’
We use nanofabricated microfluidic structures to pattern spatial boundaries for bacteria and biomimetic vesicles with reconstituted protein networks and this evaluate the fundamental job of spatial confinement within the molecular and mobile amount. Our initiatives include things like the next:
He ceesdekker.net also uncovered time to write down quite a few publications, mail Virtually forty thousand tweets and guide a successful exploration group at Delft University of Technology. ‘It doesn’t come to feel like do the job’, he states. ‘I’m just terribly curious.’
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Presently, we also understood that it should be achievable to utilize just one semiconducting carbon nanotube to produce a transistor — and we set out to make it. We stretched individual semiconducting nanotubes throughout metallic electrodes and applied the fundamental silicon substrate being a gate electrode, setting up the basic three-terminal structure of the discipline-result transistor (Fig.
Instance (4) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is revealed in gray, the rim in the pore is highlighted in red, and a 3D rendering of your movement on the DNA rod is shown.
2001, discovery of solitary-electron transistors at place temperature dependant on nanotubes; realization of to start with logic circuits with carbon nanotube devices; and discovery from the molecular construction of DNA fix enzymes with AFM
2008, very first observation of protein-coated DNA translocation by way of nanopores; solved the origin on the electrophoretic pressure on DNA in nanopores; uncovered a major velocity enhance of microtubules in electrical fields; identified an anomalous electro-hydrodynamic orientation of microtubules; and settled the origin of noise in carbon nanotubes in liquid
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij satisfied enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever layout in 2005. (nl)